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This cluster has a high association with infection and mortality, relative to other Candida species 18,5355

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Moreover, properly harnessing the Nrf2/HO-1 axis while managing its potential pro-ferroptotic risks may help maintain redox balance and curb iron overload, thereby offering an additional strategy to alleviate ferroptosis-driven damage in OA (202)

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Nomination, Category 1 status, an advisory committee vote, and final inclusion through regulation are separate stages and should not be described as interchangeable